Karlis Arturs Moors

Karlis Arturs Moors, born in Riga, Latvia, is a 3rd year doctoral candidate in the Medical Systems Biology research group at the Christian-Albrechts-University (CAU) in Kiel, Germany. Karlis obtained his Bachelor of Science and Masters in Systems Biology from Maastricht University (NL). Karlis’ current doctoral work focuses on elucidating host-microbiome interactions using metabolic modelling approaches. His research is part of the Collaborative Research Centre 1182 that investigates the interactions of microbial communities with multicellular host organisms. The spotlight of his work is on the model organism Caenorhabditis elegans and its microbiome. Karlis uses genome-scale metabolic models and high-throughput seqiencing data to investigate how the native C. elegans microbiome protects the host against natural pathogens and which general metabolic interactions exist between the host and its microbiome. Karlis is also investigating the effect of proton-pump inhibitor (PPI) use on the human gut microbiome.

In his workflow, he uses microbial community models and human whole-body models in tandem with statistical modelling approaches to understand how the microbiome could lead to the observed negative health outcomes associated with PPI use.